MSM stands for methylsulfonylmethane, a sulfur-containing compound that naturally occurs in small amounts in foods such as vegetables, fruit, grains, and milk. In supplement form, MSM is used because of its pure form of organically bound sulfur.

MSM is synthetically produced, with a structure identical to the natural form found in, for example, vegetables. The result is a pure form of sulfur that is free from the odor often associated with other sulfur sources.

MSM is an organic form of sulfur, while sulfate is an inorganic sulfur compound that is absorbed less efficiently by the body.

With daily use of one tablet, a package of 60 tablets lasts about two months. The 120 tablet package lasts four months.