Creatine monohydrate is a combination of creatine and water in solid form. It is the most used and widely available form of creatine in supplements.

Creatine monohydrate is stable, dissolves well, and has a simple structure. This makes it practical to use and it is offered worldwide as the standard form of creatine.

Other forms of creatine often have a slightly different structure or addition (such as acids or esters) but are generally used less widely. Creatine monohydrate has been in use the longest and is the most well-known among users.

Creatine is a natural substance found in small amounts in animal foods, such as meat and fish.